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Bill Downs
Bill Downs is an expert on diet and digestion.
Bill is the author of the Trafon (spell it backwards) blog

Bill has unsurpassed knowledge of how nutrients help the body heal. Involved with nutritional information for over 20 years, Bill has lectured worldwide, is a published author, and has penned a number of papers in cited peer-reviewed scientific journals. A recognized expert in his field , Bill has had over 75 TV , Radio and Newspaper interviews. Bill's five years of post-graduate education in Nutrition Science and Biological Chemistry along with his years of clinical experience as a nutrition consultant have given him great insight into the modern human condition, the needless suffering of people, and a profound appreciation for the body's miraculous capabilities to heal itself when properly supported by nutrition.

In The News

World Health Organization and the Food and Agriculture Organization of the United Nations states; probiotics are "live microorganisms which when administered in adequate amounts confer a health benefit on the host".

"In conclusion, probiotics act as an adjuvant in the prevention and treatment of a wide variety of chronic diseases" (from a paper presented by Broekaert and Walker of Harvard Medical School , Mucosal Immunology Laboratory, Massachusetts General Hospital for Children

Elderly people should take probiotic supplements, according to scientists.

One a Meal

Intestinal Transit
Research has shown that regular daily consumption of certain probiotics optimizes functioning of the gastrointestinal tract by regulating intestinal transit time (Marteau et al., 2002; Meance et al., 1999;). Regulation of intestinal transit time, especially in people with slow transit, can improve occasional constipation states. Bacteria in the colon can transform undigested carbohydrates to short chain fatty acids, which reduces the pH of the colon and increases the osmolarity of the medium. Together, this may result in an increase in stool volume and weight, and a reduction in stool consistency. Studies show that the reduction in constipation, improves overall well-being and quality of life for the patient (Zunft HJ et al., 2004).

Clinical Studies
Below are abstracts of referenced clinical studies from the PubMed site , a service of the Unite States National Library of Medicine and the National Institute of Health.

Bifidobacterium Animalis Strain DN-173 010 Shortens the Colonic Transit Time in Healthy Women:
a double-blind, randomized, controlled study
Marteau P, Cuillerier E, Meance S, Gerhardt MF, Myara A, Bouvier M, Bouley C, Tondu F, Bommelaer G, Grimaud JC.
Gastroenterology Department, European Hospital Georges Pompidou, Paris, France. philippe.marteau@egp.ap-hop-paris.fr

BACKGROUND: A previous study has suggested that Bifidobacterium animalis DN-173 010 shortens the colonic transit time in women. AIM: To confirm this effect and to determine whether modifications of the faecal bacterial mass and/or faecal secondary bile salts may be the explanation. METHODS: A double-blind, cross-over study was performed. Thirty-six healthy women were studied in four consecutive 10-day periods. During periods 2 and 4, they ingested three 125 g cups per day of a fermented milk which was either a product containing B. animalis DN-173 010 or a control without bifidobacteria. Periods 1 and 3 were run-in and washout periods, respectively. The total and segmental colonic transit times were assessed using a pellet method. In 12 subjects, all stools were collected and analysed for pH, faecal weight, bacterial mass and bile acids. RESULTS: The total and sigmoid transit times were significantly shorter during dosing with B. animalis compared to the control period. The other transit times, faecal weight, pH, bacterial mass and bile acids were not significantly affected. CONCLUSIONS: B. animalis DN-173 010 shortens the colonic transit time in healthy women. This effect is not explained by modifications of the faecal bacterial mass or secondary bile acids.

Recent Advances in the Use of Functional Foods: Effects of the Commercial Fermented Milk with Bifidobacterium Animalis Strain DN-173 010 and Yoghurt Strains on Gut Transit Time in the Elderly
Meance S., Cayuela C., Raimondi A., Turchet P., Lucas C., Antoine J-m.
Fermented milk products containing the probiotic strain Bifidobacterium Animalis DN-173 010 (BM) have a beneficial effect in reducing gut transit times in a range of populations including adults and the elderly, especially female. The aims of this study were to investigate the efficacy of one and two servings per day of BM in elderly subjects and to determine the duration of the reduction in transit times after stopping consumption of the product. This was a randomized controlled and open study with four groups; 200 elderly subjects (aged 50-75 years) were enrolled in the trial. In all, 100 subjects with medium transit times (MTT, 40-50 h) and 100 with slow transit times (STT, >50 h) were randomized to receive either 125 g or 250 g BM daily for 2 weeks. Oro-faecal gut transit was determined by the use of coloured markers. Both dosages significantly reduced oro-faecal transit time with reductions of 20.5% and 42.2% observed in MTT subjects receiving BM 125 g/day and 250 g/day, respectively (p<0.0001). Corresponding reductions in STT subjects were 27.7% and 38.1%, respectively. The beneficial effects of BM lasted long after consumption of the product was stopped, with values returning to baseline in subjects with MTT at 6 weeks follow-up and in STT subjects consuming 125 g/day BM at 4 weeks follow-up. Significant differences in transit times were still observed at week 6 of follow-up in STT subjects receiving 250 g/day BM. This study completes and confirms the dose-dependent effects of BM from 0 to 250 g per day and can be compared with similar results obtained with 250 to 375g per day in a previous study on transit times in elderly subjects. It also demonstrates that there are significant beneficial effects long after consumption of the product has stopped. The results suggest an important role for this probiotic dairy product in fundamentally modulating gastrointestinal function that could beneficially affect the host, and hence reduce the susceptibility to conditions associated with delayed gut transit.

Symbiotic Containing Bifidobacterium Animalis and Inulin Increases Stool Frequency in Elderly Healthy People
Zunft HJ, Hanisch C, Mueller S, Koebnick C, Blaut M, Dore J.
Dept Intervention Studies, German Inst of Human Nutrition Potsdam-Rehbruecke, D-14558 Nuthetal, Germany.

Background: the aim of the study was to investigate the effect of a symbiotic on gut microbiota and bowel habits. Methods: a double-blind, placebo-controlled, randomized crossover study was conducted in healthy elderly people (n= 49; mean age 70 +/- 4 years) over a total of sixteen weeks divided into periods of 4 weeks each, (1) run-in, (2) first intervention, (3) wash-out, and (4) second intervention. During the intervention periods study participants consumed daily sachets either containing the symbiotic or a placebo. The symbiotic contained bifidobacterium animalis and inulin. During the whole study subjects regularly completed questionnaires on bowel habits, well-being, gastrointestinal quality of life and underwent a medical examination. At the end of each intervention period the volunteers reported their dietary intake using a 4-day food record and provided a fresh faecal sample for the analysis of microbial and other parameters. Results: the habitual dietary intake remained constant over the entire period of investigation. The consumption of the symbiotic resulted in a significant increase of stool frequency compared to the placebo period (8.8 vs. 8.1 stools per week; p < 0.05). Among other gastrointestinal symptoms, e.g. Bloating, flatulence, no differences between the treatment and placebo periods could be found. For several parameters of well-being a significant positive influence of the symbiotic treatment could be demonstrated. The characterization of the microbial composition using fluorescence in-situ hybridization and enzymatic analyses are in progress. Conclusion: the administration of a symbiotic consisting of bifidobacterium animalis and inulin improves well-being and gastrointestinal quality of life in elderly subjects.

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Did You Know?

You carry around three pounds of bacteria (both "good" and "bad" types) in your intestines every day of your life.?

There are about 400 different species of bacteria residing in your digestive tract?

That these bacterium number in the trillions?

That PROBIOTICS (good bacterium) are an INTREGAL part of your digestive system and are ESSENTIAL for good health?

That the ratio of good bacteria to bad in a HEALTHY gastrointestinal tract is 85 percent versus 15 percent, respectively?

People over 60 have about 1,000-fold LESS "friendly" bacteria in their guts compared with other adults

That your diet, prescription drugs (especially antibiotics), stress, and illnesses, can kill your essential good bacteria?

That enzymes are present in every cell of your body?

That enzymes are NECESSARY to your food digestion, energy production, tissue and organ repair, and toxic waste removal?

That due to a nutrient depleted diet , most Americans lack sufficient types and quanities of CRITICAL to health levels of both enzymes and probiotics?

That Trafon OneAmeal™ contains the hightest premium quality strains of HEALTH promoting probiotics and enzymes CRITICALLY required by your body?
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