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Why should I try Trafon OneAmeal™ ? Trafon OneAmeal™ is a NEW Digestant Technology created by a leading expert in the field , Bill Downs. Trafon OneAmeal™ employs the highest quality, premium research grade ingredients (very expensive and not readily available). In addition, meticulous care is employed during the manufacturing process. The level of quality controls used in the manufacturing of Trafon OneAmeal™ far exceed the standards of the industry and are rarely , if at all, used by others. Below are abstracts of reference to some of the ingredients found in Trafon OneAmeal™ Alternative Medicine Review August 7,2002 Description Lactobacillus sporogenes is a gram-positive, spore-forming, lactic-acid producing bacillus. It was originally isolated and described in 1933. The organism requires a complex mixture of organic substrates for growth, including fermentable carbohydrates and peptides. Pharmacokinetics Subsequent to oral administration, L. sporogenes passes through the stomach in its spore form and upon arrival in the duodenum, germinates and multiplies rapidly. Estimates suggest the average duration of time between oral dosing and germination is four hours. After germination, L. sporogenes is metabolically active in the intestines, producing lactic acid. L sporogenes is considered a semi-resident, indicating it takes up only a temporary residence in the human intestines. Spores of L. sporogenes are excreted slowly via the feces for approximately seven days after discontinuation of administration. Mechanisms of Action Despite the transient nature of this organism in the digestive tract, the changes this lactic acid bacillus produces shift the environment in support of a complex gastrointestinal flora. The mechanism of action is presumed to be a result of improving gastrointestinal ecology by replenishing the quantity of desirable obligate microorganisms and antagonizing pathogenic microbes. Two isomeric forms of lactic acid can be produced by lactic acid-producing bacteria--dextrorotatory (D (-)) lactic acid and levorotatory (L(+)) lactic acid. L(+) lactic acid is completely metabolized in the body; however, D(-) lactic acid is not completely metabolized, resulting in a degree of metabolic acidosis. L. sporogenes produces only L(+) lactic acid. L. sporogenes is assumed to produce bacteriocins and short chain fatty acids. As the organism grows, it assimilates and incorporates cholesterol into its cellular structure. L. sporogenes possesses significant [beta]-galactosidase (lactase) activity in vitro. Lipid Disorders Administration of L sporogenes to rabbits resulted in a 90-percent inhibition in the rise of serum cholesterol secondary to feeding of high cholesterol diets. Oral L. sporogenes supplementation (360 million spores/day) decreased total serum cholesterol from an average of 330 mg/dL to 226 mg/dL in 17 subjects with type II hyperlipidemia over a three-month time interval. HDL-cholesterol increased slightly. No changes in serum triglyceride levels were observed. Digestive Disorders In laboratory animals with bacterial dysbiosis, L. sporogenes supplementation inhibits growth of pathogenic microorganisms and results in renewal of desirable obligate gastrointestinal organisms to normal levels. Reports suggest that supplementation produces a rapid resolution of acute gastrointestinal infection induced by pathogenic bacteria in calves) It has been reported that the efficacy of treatment in patients with bacterial dysbiosis receiving L sporogenes was 20-30 percent higher than traditional probiotics such as Lactobacillus acidophilus of Bifidobacteria. Seventy percent of individuals suffering from chronic constipation treated with 300-750 million spores per day of L. sporogenes for two to 10 days experienced an amelioration of abdominal distention and a normalization of stools. Reports suggest a benefit in neonatal diarrhea. Aphthous Stomatitis Reports suggest efficacy in the treatment of aphthous stomatitis with resolution occurring within two to three days. Vaginitis Vaginal administration of L. sporogenes was investigated in non-specific vaginitis. Subjects with Trichomonas or Candida vaginitis were excluded from the study. Complete relief of pruritis and discharge was reported by 93 percent of subjects. Postmenopausal subjects had a slower response to therapy. Toxicity and Side Effects Acute toxicity studies in animals have been conducted with doses as high as 50 g/kg for seven days. No abnormalities, either during supplementation or in the period after withdrawal of the supplement, were observed. Chronic supplementation of doses as high as 5 g/kg for 15 months in animals results in no observed toxicity. In humans, adverse reactions following supplementation have not been reported. Dosage A reasonable dose is 100 mg two to three times daily. Each 100 mg contains approximately 1.5 billion colony-forming units. Return Glucanase, Xylanase, Pectinase, and Phytase are all digestive enzymes. Glucanase or Beta-glucanase, breaks down polysaccharides and fibers known as beta-glucans. Xylanase breaks down the sugar xylose. Pectinase breaks down carbohydrates such as pectin that can be found in most fruits. Phytase breaks down carbohydrates, specifically phytates (phytic acid), present in many difficult to digest grains and beans. Especially useful for those suffering from serious bowel disorders which result in an inability to handle phytates from soy and gluten from wheat, oats, rye and barley. Phytase may increase mineral absorption and the bioavailability of iron, zinc, calcium, and magnesium. Return Bifido Bacterium Longum Lactobacillus Helveticus , Lactobacillus Rhamnosus , Bifido Bacterium Longum are probiotics. Probiotics, friendly microorganisms, are essential in helping to maintain the body's delicate microbial balance; an often overlooked yet critical element to your well-being. The particular strains of Lactobacillus Helveticus , Lactobacillus Rhamnosus and Bifido Bacterium Longum found in Trafon OneAmeal™ are custom designed and clinically proven to synergistically provide benefits in the areas of nutrition, digestion and immunity, protecting your body from the stresses of modern living. Theses lactic acid bacteria (LAB) probiotics help to break down the lactose found in dairy products, making it easier for those who are lactose intolerant to include nutritious dairy products in their diet. In addition, LAB manufacture the essential vitamins B1, B2, B6, B12, niacin, folic acid, and pantothenic acid, and synthesize enzymes that increase the digestibility of protein. These probiotic strains have demonstrated efficacy in helping to relieve bowel discomforts such as irregularity, bloating, pressure, flatulence and diarrhea by regulating bowel movement by moderating intestinal peristalsis. In addition they are documented to help renew the mucosal microflora throughout the gastrointestinal tract. The end result is improved digestion, with less pain and flatulence, and other symptoms of gastro-intestinal distress. Also these probiotic strains assist the immune system in numerous ways, including: In conclusion, these probiotic supplements replenish the microflora of the intestinal mucosa thus helping prevent and alleviate dysbiosis, dysbacteriosis and school related illnesses in children. They also help prevent and alleviate traveller's diarrhea, antibiotic associated diarrhea, occasional irregularity, and other gastro-intestinal disturbances, all the while stimulating the immune system. Return Proteases (proteinases, peptidases, or proteolytic enzymes) are enzymes whose catalytic function is to break peptide bonds between amino acids of proteins. The process is called proteolytic cleavage, a common mechanism of activation or inactivation of enzymes, especially those involved in blood coagulation or digestion. Proteases use a molecule of water to hydrolyze (breakdown) the peptide bonds and are thus classified as hydrolases. Proteases differ in their ability to hydrolyze various peptide bonds. Each type of protease has a specific kind of peptide bond it breaksdown. Examples of proteases include: fungal protease, pepsin, trypsin, chymotrypsin, papain, bromelain, and subtilisin. The main digestive responsibility of these proteolytic enzymes is to breakdown the protein foods you eat, which are probably one of the most difficult substances to metabolize, to liberate the amino acids needed by your body. Because of this, proteases ares considered to be one of the most important enzymes that you have. If your digestive process is incomplete, undigested protein can wind up in your circulatory system, as well as in other parts of your body. Proteolytic enzymes have been used for a long time in various forms of therapy. Their use in medicine is gaining more and more attention as several clinical studies are indicating their benefits in oncology, inflammatory conditions, blood rheology control, and immune regulation. Several studies have shown that ingested enzymes can be absorbed into the blood stream while still maintaining their enzymatic ability. When you take protease in higher quantities, it can help to clean up your body by removing the unwanted protein from your circulatory system. This will help to clean up your blood stream, and restore your energy and balance. One of the tricks of invading pathogens (bad microorganisms) is to wrap themselves in a large protein shell that your body would view as being "normal". Large amounts of protease can help to remove this protein shell, and allow your body's defense mechanisms to go into action. With the protective protein barrier removed, your immune system can step in and destroy the invading organism. Additional amounts of protease are also helpful in fighting such things as colds, flu's, and cancerous tumor growths. Protease helps in the healing and recovery from cancer by dissolving the fibrin coating on cancer cells, and thereby giving your immune system a chance to do its job. Protease can effectively shrink these tumors by helping to remove the dead and abnormal tissues, and by stimulating healthy tissue growth. Return 
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